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Monday, Feb 5th
10:00 AM – 12:00 PM
EST
Nucleic Acid-Targeted Therapeutics
Room/Location: 206AB
Dominic Reynolds, PhD (he/him/his)
– Remix Therapeutics
New Modalities (Room 206AB)
Sponsored By
Monday, Feb 5th
10:00 AM – 10:30 AM
EST
Small molecule proximity-induced targeted RNA degraders as research tools and antiviral agents
Room/Location: 206AB
Sigitas Mikutis, PhD
– University of Cambridge
New Modalities (Room 206AB)
Sponsored By
Monday, Feb 5th
10:30 AM – 11:00 AM
EST
Oligonucleotide modalities in RNA Therapeutics: the critical steps of target Identification and oligonucleotide design in drug discovery
Room/Location: 206AB
Konstantina Skourti-Stathaki, PhD (she/her/hers)
– N-Lorem Foundation
New Modalities (Room 206AB)
Sponsored By
Monday, Feb 5th
11:00 AM – 11:30 AM
EST
Expansions of Friedreich's ataxia GAA•TTC repeats: role of DNA replication and prevention by LNA-DNA oligonucleotides
Room/Location: 206AB
Sergei Mirkin, PhD (he/him/his)
– Tufts University
New Modalities (Room 206AB)
Sponsored By
Monday, Feb 5th
11:30 AM – 12:00 PM
EST
Reprogramming RNA to target unaddressed disease drivers
Room/Location: 206AB
Dominic Reynolds, PhD (he/him/his)
– Remix Therapeutics
New Modalities (Room 206AB)
Sponsored By
Monday, Feb 5th
3:00 PM – 5:00 PM
EST
Induced Proximity Beyond Degradation
Room/Location: 206AB
Nancy K. Pryer, PhD
– Ambagon Therapeutics
New Modalities (Room 206AB)
Sponsored By
Monday, Feb 5th
3:00 PM – 3:30 PM
EST
Discovery of small molecule molecular glues stabilizing disease-driving proteins to the 14-3-3 adaptor proteins for novel cancer therapeutics
Room/Location: 206AB
Nancy K. Pryer, PhD
– Ambagon Therapeutics
New Modalities (Room 206AB)
Sponsored By
Monday, Feb 5th
3:30 PM – 4:00 PM
EST
Covalent hit discovery using DNA-encoded library technology
Room/Location: 206AB
Paige Dickson, PhD (she/her/hers)
– X-Chem
New Modalities (Room 206AB)
Sponsored By
Monday, Feb 5th
4:00 PM – 4:30 PM
EST
HiBiT cellular thermal shift assays: Learnings from two high-throughput screening campaigns
Room/Location: 206AB
Sophia Katherine Berry, Dr
– AstraZeneca
New Modalities (Room 206AB)
Sponsored By
Monday, Feb 5th
4:30 PM – 5:00 PM
EST
Reimagining Druggability using Chemoproteomic Platforms
Room/Location: 206AB
Daniel Nomura, PhD
– University of California, Berkeley
New Modalities (Room 206AB)
Sponsored By
Tuesday, Feb 6th
10:00 AM – 12:00 PM
EST
Difficult Targets: Expanding Target Space
Room/Location: 206AB
Amine Sadok, PhD
– Amgen
New Modalities (Room 206AB)
Sponsored By
Tuesday, Feb 6th
10:00 AM – 10:30 AM
EST
Integrating Artificial Intelligence and Traditional Screens for Targeting “Undruggable" Cancer Targets
Room/Location: 206AB
Igor Stagljar, PhD
– University of Toronto School of Medicine
New Modalities (Room 206AB)
Sponsored By
Tuesday, Feb 6th
10:30 AM – 11:00 AM
EST
RAPID – photoaffinity-based high-throughput ligand discovery in cells
Room/Location: 206AB
Matt Labenski, PhD (he/him/his)
– Jnana Therapeutics
New Modalities (Room 206AB)
Sponsored By
Tuesday, Feb 6th
11:00 AM – 11:30 AM
EST
Targeting ubiquitin protease system to treat MYC-driven breast cancer
Room/Location: 206AB
Sudhakar Jha, PhD (he/him/his)
– Oklahoma State University, College of Veterinary Medicine, Stillwater, OK, USA
New Modalities (Room 206AB)
Sponsored By
Tuesday, Feb 6th
11:30 AM – 12:00 PM
EST
Sorafenib and Lenvatinib induce vascular responses in patient derived HCC on-Chip models
Room/Location: 206AB
Bas Trietsch
– PhD
New Modalities (Room 206AB)
Sponsored By
Tuesday, Feb 6th
3:00 PM – 5:00 PM
EST
Next Generation Protein Therapeutics
Room/Location: 206AB
Jamie Spangler, PhD
– Johns Hopkins University
New Modalities (Room 206AB)
Sponsored By
Tuesday, Feb 6th
3:00 PM – 3:30 PM
EST
Engineering cytokine/antibody fusion proteins as targeted immunotherapeutics
Room/Location: 206AB
Jamie Spangler, PhD
– Johns Hopkins University
New Modalities (Room 206AB)
Sponsored By
Tuesday, Feb 6th
3:30 PM – 4:00 PM
EST
Engineering High Avidity, Low Affinity (HALA) Antibodies to Auto-Tune the Delivery of Antibody Drug Conjugates In Vivo
Room/Location: 206AB
Greg Thurber, PhD (he/him/his)
– University of Michigan
New Modalities (Room 206AB)
Sponsored By
Tuesday, Feb 6th
4:00 PM – 4:30 PM
EST
Continuous Protein Evolution Enabled by Machine Learning and Laboratory Automation
Room/Location: 206AB
Nilmani Singh, PhD (he/him/his)
– University of Illinois Urbana-Champaign
New Modalities (Room 206AB)
Sponsored By
Tuesday, Feb 6th
4:30 PM – 5:00 PM
EST
Orchestrated Laboratory Robotics: Development of 3rd Generation Robotics for Biologics Development
Room/Location: 206AB
Thomas E. Albanetti, Jr., MS (he/him/his)
– AstraZeneca
New Modalities (Room 206AB)
Sponsored By
Wednesday, Feb 7th
9:30 AM – 11:30 AM
EST
Biomolecular Condensates
Room/Location: 206AB
SANGRAM S. PARELKAR, PhD
– Dewpoint Therapeutics
New Modalities (Room 206AB)
Sponsored By
Wednesday, Feb 7th
9:30 AM – 10:00 AM
EST
Leveraging automation and AI for high-throughput discovery of condensate-modifying drugs
Room/Location: 206AB
SANGRAM S. PARELKAR, PhD
– Dewpoint Therapeutics
New Modalities (Room 206AB)
Sponsored By
Wednesday, Feb 7th
10:00 AM – 10:30 AM
EST
Novel Phase Separation Modifying therapeutics target Biomolecular interactions to unlock difficult- to-drug proteins
Room/Location: 206AB
Bahareh Eftekharzadeh, PharmD, PhD (she/her/hers)
– Nereid Therapeutics
New Modalities (Room 206AB)
Innovation Award
Sponsored By
Wednesday, Feb 7th
10:30 AM – 11:00 AM
EST
Identification of Small Molecule Inhibitors of hyperphosphorylated tau (p-tau) Aggregation Via High Throughput Screening
Room/Location: 206AB
Virneliz Fernandez Vega, B.S.
– The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology
New Modalities (Room 206AB)
Sponsored By
Wednesday, Feb 7th
11:00 AM – 11:30 AM
EST
Screen for Modulation of Nucleocapsid Protein Condensation Identifies Small Molecules with Anti-Coronavirus Activity
Room/Location: 206AB
Timothy Mitchison, PhD (he/him/his)
– Harvard Medical School
New Modalities (Room 206AB)
Sponsored By
Wednesday, Feb 7th
12:30 PM – 2:30 PM
EST
Emerging Drug Discovery Technologies
Room/Location: 206AB
Abhijit Bhat, PhD
– RayzeBio
New Modalities (Room 206AB)
Sponsored By
Wednesday, Feb 7th
12:30 PM – 1:00 PM
EST
Advancing the science of Radiopharmaceutical Therapy : a renewed hope for new cancer treatments
Room/Location: 206AB
Abhijit Bhat, PhD
– RayzeBio
New Modalities (Room 206AB)
Sponsored By
Wednesday, Feb 7th
1:00 PM – 1:30 PM
EST
Alpha Emitters — Decay Chains, Chelation Chemistry & Radiopharmaceuticals — An Overview
Room/Location: 206AB
David Bauer, PhD
– Memorial Sloan Kettering Cancer Center
New Modalities (Room 206AB)
Sponsored By
Wednesday, Feb 7th
1:30 PM – 2:00 PM
EST
Rapid optimization of small molecules using a fusion of physics-based simulations, AI and parallel chemistry
Room/Location: 206AB
Brian Chamberlain, PhD (he/him/his)
– TandemAI
New Modalities (Room 206AB)
Sponsored By
Wednesday, Feb 7th
2:00 PM – 2:30 PM
EST
Radiotheranostic development from lab to clinic – challenges and opportunities.
Room/Location: 206AB
Sean Carlin, PhD (he/him/his)
– Invicro
New Modalities (Room 206AB)
Sponsored By