aµtoPulse Tangential Flow Filtration: High-throughput sample processing with the world's lowest volume TFF.

This presentation will introduce our newest product, the aµtoPulse - TFF System. The aµtoPulse is a fully automated, walk-away system that uses Tangential Flow Filtration (TFF) for high-throughput sample concentration and buffer exchange at the lowest TFF hold-up volume in history: 250 µL.

The aµtoPulse predecessor, the µPulse® TFF system, has been a workhorse for labs around the world processing proteins/MAbs, LNPs, RNAs, DNAs, and Viruses/VLPs since 2022. The intuitive workflow and optimized process eliminate time lost manually concentrating and buffer exchanging your samples. While the µPulse excels in single-sample processing, researchers need a way to scale to higher throughput.

Codesigned with our µPulse customers, this new system takes our patented millifluidic TFF technology to the next level. Users can automatically process samples in parallel while maintaining individual sample process control. We will go through the key features of this system and how it compares to its predecessor, the µPulse® TFF System, including applications, process controls, and paradigm-shifting innovations.