Quickly identifying the most promising hits and leads with "drug-like" properties is one of the main challenges in drug discovery and relies on robust hit finding and profiling strategies. In this session, we will discuss innovative therapeutic approaches with a first case study on protein degraders design. A second case study will focus on label-free technological advances to drive High Throughput Screening (HTS) projects using, for example, the Echo® MS.
Key Takeaways • Learn how we design protein degrader strategies, including the visualization of ternary complex using biophysics. • Gather valuable information on the optimization of screening cascades with reduced assay set-up time and enzyme consumption using the Echo MS. • Meet our experts in person and deepen your knowledge in hit finding from HTS to extended hit characterization.
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