Traditional antibody discovery relies on analytical instruments that require significant hands-on time, quantities of sample, capital equipment, and specialized expertise. In this Tutorial we will demonstrate how the Nicoya Alto® is an ideal platform for antibody characterization at every step of the discovery process and for a broad range of applications. Learn how researchers at UCLA selected optimal anti-idiotype antibodies from a pool of tens of thousands of hybridomas in record time. From only 2 µL of crude sample, see how it's possible to perform screening, quantitation, kinetics, and binning to fully characterize and select the best antibodies. Learn how data quality and throughput are maximized using the latest advances in digital microfluidics to eliminate artifacts, optimize accuracy, and automate tedious, error prone sample prep. Get a sneak peek of soon-to-be-launched features, and see a live demo of the Nicosystem, Alto’s powerful cloud based software platform for antibody discovery.