Abstract: In pursuit of alignment with AstraZeneca's sustainability objectives, our collaboration with Grenova aimed to assess the efficacy of the Purus microplate washer. This study primarily sought to evaluate its capacity for effectively cleansing microplates, potentially facilitating AstraZeneca in adopting a microplate reuse approach. This transition holds the promise of diminishing both solid waste generation and carbon emissions. Our investigation encompassed a comprehensive analysis involving diverse microplate types and a range of assays. Through meticulous refinement of the washing procedures, the Purus microplate washer exhibited a progressive enhancement in its performance. This advancement translated to a notable reduction in the quantifiable number of compounds as determined by LCMS analysis. Anticipating the future, there are ongoing deliberations about a continued partnership aimed at optimizing plate-cleaning protocols to further enhance assay plate decontamination. This cooperative effort holds significant potential for refining the plate reusability strategy.
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