Browse by Track

(1012-A) A novel single-cell fluorescence microscopy-based analysis for the detection of biomarkers of cellular senescence

(1029-B) Characterization of membrane protein using mass spectrometry-based technologies — affinity selection-mass spectrometry (AS-MS)

(1034-C) Doing more with less: Application of microsampling, LC/MS/MS and MS imaging for the measurement of drug, metabolites and lipid biomarkers in biofluids and tissues

(1035-D) Free cysteine profiling confirmed STING target engagement and identified potential covalent off-targets for a novel STING inhibitor

(1046-C) HymonBio’s Leading PCR Trends: MoLock and One-Step Technology

(1053-B) High-throughput intact protein analysis using Acoustic Ejection Mass Spectrometry (AEMS) on a quadrupole time of flight mass spectrometer

(1090-C) Development of Tumor and Blood Pharmacodynamic Assays to Support Development of IACS-53152, a Protein Arginine Methyltransferase 1 Inhibitor

(1092-A) Paper-Based Vertical Flow Immunoassay for the Point-of-Care Multiplex Detection of Radiation Dosimetry Genes

(1172-A) Laser-treated thermoplastic carbon electrodes for enhanced performance of electrochemical sensors

(1262-C) Development and characterization of a novel monoclonal antibody to Tau p217 in Alzheimer’s disease murine models and human disease tissue

(1265-B) Development of a cross platform IR-MALDESI front end for high throughput ToF Mass Spectrometry

(1297-B) Generating affinity reagents to phosphoepitopes by phage-display

(1363-D) quantum-based sensing of microRNA biomarkers of breast cancer using NV-center nanodiamonds.

(1387-D) Towards a plasmonic nanosieving device for the automated selection of cancer-relevant peptides targeted by T-cell receptor-mimic antibodies

(1389-B) Ultra-High Throughput Sample Quality control enabled by Sciex Acoustic Ejection Mass Spectrometry (AE-HRMS) Technology

(1000-A) A High-Throughput Compatible Live-Virus Human Spheroid-Based Screening Platform to Identify Antiviral Compounds Against Viruses with Pandemic Potential

(1001-B) A comprehensive influenza reporter virus panel for high-throughput deep profiling of neutralizing antibodies

(1002-C) A Next-Generation, Cloud-based Viral Infectivity Assay for Rapid, High-Throughput Screening of Vaccines and Antivirals

(1003-D) Characterization and comparison of hypoxia inducing factors on tumor growth and metastasis in 2D and 3D tumor models

(1005-B) A Novel Quantitative High Throughput Screening (qHTS) Assay for Human Neurotoxicity Using 3D-suspension Culture of Dopaminergic Neurons

(1006-C) A Rapid Method for Simultaneously Determining an Optimal Buffer and the LLOQ of a Small Molecule, a Peptide and a Protein Using a Liquid Handler and an Acoustic Ejection-Enabled QTOF Mass Spectrometer

(1007-D) A Rapid, High-Throughput and Effective Process for Identifying Molecular Glues Using Affinity Selection Mass Spectrometry (ASMS)

(1008-A) A non-faradaic, point-of-care, multiplex, electrochemical wound healing biosensor for profiling of regenerative biomarkers

(1009-B) A Real-Time Cellular Thermal Shift Assay to Monitor Target Engagement

(1147-D) A validated Method For the Quantification of Protacs – 3 – Gefitibib in Rat Plasma to Support Rodent PK Studies

(1014-C) Automated and high-throughput T-cell immunophenotyping assays using Celigo and Cellaca PLX image cytometers

(1015-D) Alternative cell counting and viability detection using NexGreen/PI fluorescent stain on multiple low- and high-throughput image cytometry platforms

(1019-D) Automated technique to examine the cell viability of 3D cancer spheroids using the the OT-2

(1021-B) AutoHCS: AI-based scoring of high-content screens results in morphological clustering that predicts mechanisms of action.

(1025-B) Automating selection of engineered target cell lines for Chimeric Antigen Receptor T cells

(1026-C) Cross-platform assessment of high-throughput mass-spectrometry based quality control of compound libraries

(1027-D) Developing a multiplex assay to monitor apoptosis and necrosis using the Cellaca® PLX Image Cytometer

(1033-B) Extracellular ATP measurement in real time using live cells

(1041-B) Engineered human neuromuscular junction- on-a-chip platform as a drug development tool supporting development of therapies

(1042-C) High throughput end-to-end automation of Pan Cancer HuID workflow provides high quality, consistent results from plasma samples with various cancer mutations

(1043-D) High-throughput 3D spheroid co-culturing platform for screening of organ-organ interactions

(1048-A) Development of a MALDI-TOF MS high-throughput capable screening assay for iPSC macrophage phenotyping and drug compound characterization

(1052-A) Electric field-Assisted Automatable Dried Blood Spots Sample Preparation device for Neonatal Abstinence Syndrome Screening

(1054-C) Multiplexed Cardiomyopathy and Proarrhythmia (Cardiotoxicity) KIC Assay of Human iPSC-Cardiomyocytes

(1055-D) • nELISA High-Throughput Protein Profiling of Adipocytes Provides Mechanistic Insights into Immunometabolism

(1056-A) Live Cell Painting: Drug Responses in Human Primary Patient Cells with a New Nontoxic Dye

(1057-B) In vitro cytotoxicity and genotoxicity of chalk dust particles generated in South African class rooms

(1059-D) ReFRAME: Empowering Drug Repurposing Through an Open-Access Library of 12,500 Compounds for Broad-Spectrum High-Throughput Screening

(1062-C) Pooled image-based phenotypic compound screening in human cells enabled by Ghost Cytometry with DNA barcoding technology

(1063-D) The power of high-throughput high, content screening in condensate-based drug discovery

(1064-A) High-throughput characterization of isozyme-specific Aldehyde Dehydrogenase (ALDH) inhibitors

(1065-B) Plate-based screening approaches and mechanistic insights to inform optimization of PROTAC® degraders for the treatment of neurodegenerative disease

(1066-C) Targeted LC-MS with Automated Sample Preparation Enables High-Throughput Screening Assessment of the Conjugatability of SMARTag® Peptides

(1068-A) Identification of small molecules targeting FoxP3 by high-throughput drug screening: search for specific regulators

(1069-B) SARS2 Entry Helix Bundle HTS Campaign

(1070-C) Development of a high-throughput image cytometric screening method as a research tool for immunophenotypic characterization of patient samples from clinical studies

(1071-D) High-throughput SARS-CoV-2 antiviral testing method using Plate-Based Image Cytometer

(1072-A) Increasing protein extraction throughput for cell-based assays; integration of an AFA-assisted ultrasonication and an automated liquid handling workstation to study biological perturbations

(1073-B) Measuring apoptotic effects of EP4A1 and EP4A2 on Kuramochi with a high-throughput multiplex image cytometric method

(1074-C) 3D Brain Perfusable Vascularized Model to Study Neurotropic Flavivirus Recombinant NS1 Induced Endothelial Dysfunction

(1078-C) A novel cell-based assay to identify the FLT3 kinase construct used in enzyme inhibition assays that best represents the activity of cellular FLT3

(1081-B) High-throughput, AI-driven, pooled phenotypic CRISPR screening by ghost cytometry.

(1086-C) Revolutionizing Renal Research: Microfluidic Kidney Tubuloids-on-a-Chip for Improved Drug Translation

(1087-D) Vascular inflammation modulates Trans-Endothelial Electrical Resistance and immune cell migration in a scalable organ-on-a-chip platform

(1091-D) A Novel Sox-based Continuous and Homogeneous Assay for the Discovery of Inhibitors of Inactive and Active AKT

(1093-B) A Proven Activity-Based Workflow for the Identification and Characterization of Time-Dependent Kinase Inhibitors Using a Continuous Assay Format

(1094-C) A solution for reducing carryover signal and improving throughput of fluorescence fragment analysis on microfluidic electrophoresis platform

(1095-D) Applying the right reference standard for high throughput ssDNA size analysis

(1098-C) Citron kinase: the tasty juice of the early drug discovery

(1099-D) Development and validation of a HTS Platform for the discovery of new antifungal agents against fungal plant pathogens

(1101-B) Development of Cell-based Assays for the Identification and Characterization of Inhibitors of Mutant G323E Hypoxia Inducible Factor-2α (HIF-2α).

(1102-C) High Content Imaging Is Now High Throughput: End-to-End High Content Imaging and Subcellular Analysis of Autophagy in Minutes

(1103-D) High Content Phenotypic Screening of Cell Paint Assays on Araceli Endeavor®

(1104-A) The ultra-HTS cell lysate-based platform to discover small molecule modulators of p38/MK2 protein-protein interaction for therapeutic discovery

(1105-B) IMMUNATURAL: An HTS Platform for the discovery of small-molecules from microbial origin against the PD-1/PD-L1 protein-protein interaction.

(1107-D) The Development of a Novel Mobility Shift Analysis System for Kinase Small Molecule Drug Discovery using the SCIEX BioPhase 8800

(1122-C) Production of peroxynitrite by cancer-associated immune cells can be detected with a fluorescence-based assay

(1128-A) Active-site and allosteric cyclic peptide inhibitors of secreted M. Tuberculosis Chorismate Mutase

(1132-A) Assessing microenvironment recapitulation of a 3D printed ovarian-tumoroid-on-a-chip via PARP inhibitor treatment response

(1138-C) Quantitative Analysis of Protein Translocation using High-Content Imaging and YT-SOFTWARE

(1192-A) AlphaLISA SureFire® Ultra™ technology as a unique platform to demonstrate TREM2/DAP12 signalling cascade activation in the neuroinflammatory disease space

(1139-D) The power of combining PROTAC degraders targeting cyclin-dependent kinases (CDK4/CDK6) with AlphaLISA® SureFire® screening technology for the study of cell cycle regulation in oncology

(1141-B) Developing a High-throughput Screening Assay for Myelination and Demyelination Promoting Compounds using Human iPSC-derived Schwann cell progenitor cells, Motor Neurons and Sensory Neurons from the Same Donor

(1142-C) CRISPR knockout screening for drug target identification and validation using CRISPR-Ready ioMicroglia

(1144-A) Development of a high-throughput compatible, neuronal spheroid ALS disease model

(1149-B) A NanoBRET™ Target Engagement Assay for Querying Domain Selectivity at Full-Length Polymerase Theta in Live Cells

(1150-C) PROTAC and Molecular Glue Mediated Degradation of Neosubstrates using HiBiT-tagged Cell Lines in a High-Throughput Screening Workflow

(1152-A) Development of novel 9H-carbazole-4H-chromene molecular hybrids as multi-target directed ligands for the treatment of Alzheimer’s disease

(1153-B) Discovery and Development of Small Molecules by Information-rich Next Generation Multiplexing SPR

(1154-C) Throughput Meets Flexibility: The Next Generation Multiplexing SPR for Efficient Therapeutic Protein Discovery and Development

(1156-A) Electric-field Assisted Sample Preparation of Whole Blood and Dried Blood Spots for Steroid Quantification using LC-MS/MS

(1157-B) Practical Evaluation of Time-Dependent Inhibition Kinetics Through Small-Volume Size-Exclusion Chromatography

(1158-C) Live Cell Painting: enhancing throughput and insights in drug discovery with a novel non-toxic, mix-and-read method for high-content screening

(1161-B) Fast Kinetic Imaging and Analysis of Intracellular Dynamics in Human iPSC- derived Neurons

(1166-C) Advanced 3D Cell Models for Next Generation Therapeutics: Standardized Organoid Co-Cultures and Assays in Microwell Plates

(1167-D) Competition assay using Fluorescence Polarization to determine the Residence Times for Calcitonin and AMYR agonist, AM833

(1169-B) Measuring protein ligand binding with an endogenous HiBiT CETSA test system

(1171-D) High-Throughput Automation of Plasmid DNA Extraction Enhances Efficiency and Reliability

(1179-D) Comparison of Transient Gene Delivery Methods in Human iPSC-derived Neurons and Glia

(1182-C) Binding and Functional Characterization of Anti-HER2 Antibodies Using Advanced Flow Cytometry and BLI Label-Free Detection

(1183-D) Quantifying in vitro complement-dependent cytotoxicity (CDC) using advanced flow cytometry

(1185-B) Generation and characterisation of a panel of human iPSC-derived neurons and microglia carrying early and late onset relevant mutations for Alzheimer’s disease

(1191-D) A cell- and organelle-targetable thallium indicator for fluorescence-based ion channel assays

(1193-B) A Comparative Analysis of Compound Clustering and HIT Prediction Variability in Cell Painting Assays Using Supervised and Unsupervised Deep Learning and CellProfiler Methods.

(1195-D) A genome-scale CROP-Seq screen reveals mediators of T cell signaling

(1196-A) TracerDB: A comprehensive database of validated fluorescent probes to quantify small molecule-protein interaction in vitro and in live cells

(1198-C) A guide for reliable nucleic acid characterization in high-throughput applications

(1199-D) A live cell PRMT5 NanoBRET Target Engagement Assay querying competitive and uncompetitive modes of inhibition

(1202-C) A Platform for Novel Target Discovery - Delivering Complexity & Robustness into Arrayed Immuno-Oncology Screens at AstraZeneca

(1205-B) A walkaway solution for assessing drug effects on patient-derived cancer organoids

(1209-B) Addition of Covalent Warhead and DEL-generated Hit Fragmentation empower Fragment-Based Drug Discovery

(1211-D) Advancing Antibody Discovery with OmniAb: High-Throughput Screening with xPloration™

(1213-B) Advancing Drug Discovery through 3D Cell Models: Unveiling Novel Hits and Mechanisms

(1214-C) Advancing Gene Therapy: Integrating Automated RNA Potency Assays for Precise AAV Vector Characterization

(1215-D) Affinity Selection-Mass Spectrometry HTS Applied to Challenging Drug Targets.

(1216-A) An automated plasmid purification protocol – avoiding ancillary equipment and reducing manual intervention.

(1219-D) Applications of Open Port Sampling Mass Spectrometry to Increase Throughput

(1220-A) Applying RT-qPCR for HTS of Transcription Factors

(1222-C) At-scale Enablement of a Human Bronchial Epithelial (huBEC) Cell Air Liquid Interface (ALI) Model for Respiratory Antiviral Program Support with Potential for Improved Human Physiological Relevance

(1223-D) Automated and Open-source Biochemical Assay Method Development Using an Inexpensive Robotic Liquid Handler

(1237-B) Bioluminescent cell-based reporter identifies atypical activator of human Sonic Hedgehog Autoprocessing

(1239-D) Biophysics in Kinase Drug Discovery: from Fragment-based Screening to PROTAC Ternary Complex Characterization

(1242-C) Cell and tissue-based in vitro pulmonary fibrosis assays for identification of compounds with potential anti-fibrotic activity

(1244-A) Ceramide scoring for Cardiovascular Disease risk prediction using Agilent Rapidfire SPE-MS/MS

(1245-B) CETSA®: Accelerating Primary Screening of P53 through Rapid High-Throughput Target Engagement Technology

(1246-C) Chromatography Free Measurements Enabling Rapid Quantitation of Synthetic Cannabinoids in Urine

(1247-D) AptaFluor® SAH: A Homogenous, Universal Assay for Histone, RNA, and DNA Methyltransferases. Case Study for PRMT5, MLL4, METTL3/14, and NSP14

(1251-D) Corning Matrigel matrix Supplemented Media for Pancreatic Cancer Organoid Assays

(1252-A) CRISPR platform for Target Identification and Validation at Evotec

(1255-D) Deep characterization of binding kinetics for 210 kinase inhibitors against 80+ kinases

(1257-B) DELs to NanoBRET Probes: Enabling Cell-Active Target Engagement

(1258-C) Detection and Quantification of Cellular cGAMP using Homogenous HTS Formatted Bioluminescent Assay

(1259-D) Determination of Cell Viability using High-Dimensional Morphology Analysis

(1267-D) Development of a HiBit peptide-based nanoBRET ligand binding assay for galanin receptor 1 in the live cell

(1268-A) Development of a High Throughput Cell Based Activity Screen to Identify Inhibitors of a Complex First in Class Redox Enzyme using Acoustic Ejection Mass Spectrometry (AEMS)

(1269-B) Development of a high-throughput assay using exhausted T cells for screening immune checkpoint modulators

(1270-C) Development of an Automated Gyrolab® Generic Toxicokinetic Method for the Quantification of Human IgG-based Molecules

(1272-A) Differential binding of ∆9-tetrahydrocannabinol derivatives to type 1 cannabinoid receptors (CB1)

(1278-C) Enhancing Molecular Lab Efficiency Through Comprehensive Automation of Bioanalytical Workflows

(1282-C) Evaluation of Capillary Mediated Vitrification as an Alternative to Traditional Cold Temperature Storage for Kinase Assay Reagents

(1283-D) Facilitating combination therapy studies on-a-chip with patient-derived 3D tumour models

(1284-A) Fast Post-thaw Recovery of Cryopreserved Cells for Use in Bioassays

(1285-B) First-in-class Selectivity System for Quantitative Kinase Inhibitor Profiling in Live Cells against 192 Kinases

(1288-A) Fluorescence-based drug repurposing screen of the potassium channel, KV3.1 with V434L mutation.

(1289-B) From Paper to Assay: a Case-Study on Adapting, Developing, and Troubleshooting an Enzymatic Assay for High-Throughput Screening.

(1293-B) Functional Assays at the Single Cell Level: ​Advantages and Applications for NK Killing Assays

(1294-C) Functional Characterization of Healthy and Alzheimer’s Disease-related 3D Neurospheres Formed Using Human iPSC-derived Glutamatergic Neurons, GABAergic neurons, and Astrocytes.

(1295-D) Functional Phenotypic Excitation of Human iPSC-derived Spinal Motor Neurons Cultures from Amyotrophic Lateral Sclerosis Patients

(1296-A) Gene-Edited Induced Pluripotent Stem Cell-Derived Microglia as a Platform for Neurodegenerative Research

(1299-D) Glass-bottom Nanowell-in-microwell Imaging Plates

(1301-B) Harnessing the power of qHTS and Machine Learning for the discovery SARS-CoV-2 Papain-Like protease inhibitors

(1302-C) High content image analysis of human cortical adherent organoids: 3D MICro-brains

(1303-D) High Throughput Analytics: Automation of HPV Yeast Sample Preparation for Intracellular HPV Protein Flow Cytometry

(1304-A) High throughput production and assessment of uniform 3D cultures using the Corning® Elplasia® 12K Open Well Plate.

(1306-C) High-content immunofluorescence screen identifies ingenol-3-angelate to increase B7-H3-CAR T antigen expression on lung metastatic osteosarcoma cells

(1307-D) High-throughput Affinity Selection Mass Spectrometry Using a Novel Two Dimensional RapidFire TOF Platform

(1308-A) High-Throughput Biologics Discovery, Production, and Characterization Using Automated Workstations

(1309-B) High-Throughput Optimization of Paper-Based Cell-Free Biosensors

(1310-C) High-throughput pathway screening and target deconvolution of novel oncogenic YAP/TAZ signaling pathway inhibitors

(1311-D) High-throughput Sample Preparation Enabling Rapid Protein Quantitation via Targeted Mass Spectrometry

(1312-A) High-throughput screening using a novel HER2-positive brain metastatic breast cancer model identifies the pan-ErbB inhibitor poziotinib

(1314-C) Homogeneous Antibody-Binding Assay Using High-Throughput Microscopy

(1315-D) Homogeneous Luminescent Immunoassays for Proliferation and Senescence

(1316-A) Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation

(1317-B) Identification of broad-spectrum inhibitors against Bunyaviral endonucleases

(1318-C) Identification of compounds targeting KRAS and SHP2 from the National Cancer Institute diversity compound library with protein conformational array

(1319-D) Identifying potential adverse health effects of chemicals by screening on a panel of safety-related biological targets

(1322-C) Innovative approaches to cancer research: High-throughput screening combined with live-cell imaging for drug response analysis

(1323-D) Insights about Affinity Selection Mass Spectrometry gleaned from computational simulation

(1324-A) Insights into the dynamics of PCSK9/LDLR interaction: effect of gain-of-function mutations and pH-dependent affinity

(1325-B) Insights into the Molecular Mode of Action of Compounds Targeting Nucleases and Helicases Utilizing switchSENSE

(1326-C) Integrating Automated High-Throughput Scratch Assay and Cell Painting for Comprehensive Analysis of Cell Migration and Wound Healing

(1328-A) Introduction of Zeon Original Coating COP Microplates for Cell Imaging

(1329-B) LabChip GX II Touch system for gene therapy applications: High-throughput AAV empty/full characterization

(1332-A) Large Scale Screening of Drug Candidates from Multiple Modalities using Biophysical Technologies in Early-Stage Drug Discovery

(1333-B) Large-scale Characterization of Drug Candidates Against Transmembrane Receptors using HT-SPR

(1337-B) Lumit™ Cytokine Immunoassay Automation for High-Throughput Screening

(1339-D) MCSR-HTSC at OSU: an academic high throughput screening core facility for early cancer drug discovery

(1340-A) Method Updates in the Measurement of Heterocyclic Aromatic Amines in Human Urine using Hamilton Starlet Automated Liquid Handling Platform and LC-ESI-MS/MS

(1344-A) Microglia integrated 3D neural spheroids for disease modeling and therapeutic development

(1345-B) Miniaturization of fluorescent kinetic assay for optimal conditions: maximizing fluorescence while minimizing volume.

(1346-C) Modeling rare genetic diseases for drug discovery with C. elegans quantitative high throughput screening (qHTS)

(1349-B) Natural Product Compound Fractionization of the Lion’s Mane Mushroom and HTS Analysis of its Effects on Multiple Models of Neuronal Disorders

(1351-D) Neurotoxicity and Drug Screening Assay Characterization in Healthy and Progranulin R493X HZ KO Human iPSC-derived Induced Excitatory Neurons

(1352-A) Nuisance compound behavior in cellular assays: nonspecific membrane bilayer perturbations by ivermectin underlie SARS-CoV-2 in vitro activity

(1354-C) Optimization of high-throughput human glutathione peroxidase GPx1 and GPx4 assays for the discovery of small molecule inhibitors

(1356-A) Phenotypic Screening using hPSC Neurons on Multi-Electrode Array (MEA) with Novel Analysis Methodology combined with Genedata Screener

(1361-B) Quantitative high throughput screening methods for Rift Valley Fever Virus

(1362-C) Quantitative high-throughput screening-enabled drug repurposing identifies small molecule inhibitors of Chikungunya nsP2 protease

(1364-A) Rapid Cellular Functional Activity Profiling of Multi-Receptor Targeted Anti-Obesity Therapies

(1365-B) Reactive oxygen species detection using a luminescent cell-based assay

(1366-C) Real Time Cellular Thermal Shift Assay (RT-CETSA) Instrument Development

(1370-C) Robotics for Revolutionizing T Cell Engager Drug Discovery

(1372-A) Scalable patient derived 3d colorectal cancer organoids in high throughput applications

(1374-C) Screening for Success – Enhancing Hit Confidence from Affinity Selection Mass Spectrometry (ASMS) Screens

(1375-D) Single molecule real-time analysis of dynamic nucleic acid interactions

(1376-A) Structure-guided monitoring of the human opioid receptor family using BRET assays

(1377-B) Sustainable Vitamin A; Automating a Viability Assay to Increase Sample Processing Capacity and Gain More Insights

(1379-D) Targeting NETosis in Autoimmune Diseases

(1380-A) Ternary complex assays: Optimizing AlphaLISA Toolbox reagents for targeted protein degradation applications

(1381-B) The Best Of Both Worlds - Tailored Analysis Of Affinity Selection MS Data With A Generic Automation Engine

(1383-D) The DISCovery Centre (UK): Expanding the horizon of new automated DMTA assay possibilities.

(1384-A) The search for small molecule, non-nucleoside inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase

(1390-C) Uncovering Key Regulators of the Ewing Sarcoma EWSR1 Gene using a Genome-Wide RNAi Screen.

(1391-D) Using computational simulation to distill best practices for applying the Morrison equation to biochemical pharmacology data

(1392-A) Using DNA Encoded Library Selections and Hit Calling to Predict Target Tractability and Accelerate Portfolio Activities.

(1393-B) Using Mass Spectrometry detection to mitigate fluorescence interference and potency detection limits in a plate-based kinase assay panel.

(1397-B) Wastewater surveillance of infectious disease using an integrated handheld device

(1398-C) WaveFront Panoptic Kinetic Plate Imaging Platform for Early Phase Drug Discovery at Vanderbilt High Throughput Screening Center

(1399-D) Workflow Development for Wastewater-Based-Epidemiology via Low-Cost Metagenomic Sequencing of Antimicrobial Resistance in Sub-Saharan Africa

(1402-C) Drastically Accelerated Directed Differentiation of Human Pluripotent Stem Cells into Motor Neurons for Disease Modeling and Screening Applications

(1403-D) Interrogating RIG-I and MDA5 with the Transcreener® ADP2 Assay

(1404-A) Leveraging the Molecular Devices SpectraMax® i3x and the Transcreener® ADP2 Assay for Discovery of POLQ Helicase Inhibitors

(1406-C) Scalable and Efficient Generation of iPSC-derived Human Sensory Neurons for CIPN and Pain Research

(1017-B) Assay and Sample Preparation Automation using Robotic Liquid Handlers in Biologics Process Analytics

(1018-C) Automation enablement with liquid handler and magnetic-bead based purification methods for ultra-high throughput processing of solid tumor samples in oncology research

(1020-A) A Versatile Control System to Accelerate Digital Microfluidics Chip Prototyping for Diverse Lab-on-a-Chip Applications

(1023-D) Breaking the Bottleneck: Revolutionizing Plasmid Maxi-prep with AmMag™ Quatro

(1031-D) Digital System Validation of the inSPIRE system for Clinical Biomarker Laboratory automation

(1032-A) Capillary-based automation of preparing sequencing-ready libraries for nanopore sequencing technology.

(1037-B) Enabling High Throughput Technology for Sustainable Agrochemical Formulation Development

(1038-C) Fully automated size exclusion chromatography workflows for biomolecules with Dynamic Devices Lynx, for sample volumes of 100 µL up to 1 mL

(1039-D) Game Changing Plasmid Purification Technology: Thermo Fisher presents a High-Throughput, Centrifugation-Free method for isolating Transfection Grade Plasmid Purification

(1044-A) Developing Interchangeable Automation Modules to Assemble Robust Genome Editing Assays

(1050-C) KingFisher™ Plasmid Pro – The Freedom to do Something Else

(1061-B) Integration of Direct Nano-volume OPI-MS with Unchained Labs Junior for rapid sampling high throughput reaction screening in drug discovery

(1067-D) Transform the complexities of 3D cell culture into a reliable and translatable science: Automation of 3D organoid culture and organoid analysis.

(1076-A) Liquid-Handler-Free Automation of Library Preparation for Decentralized Next Generation Sequencing

(1077-B) A Next-Generation Automated Platform for High-Throughput Commercial Production of Plasmid DNA

(1089-B) Detection of cancer mutations from Formalin fixed Paraffin Embedded tumor tissues using high throughput nucleic acid extraction and digital PCR platform

(1106-C) Design and Creation of On-Demand Reaction Screening Kits via Unchained Labs Junior

(1110-C) Assessing the Efficacy of Pressure-Based Monitoring in Automated Liquid Handling

(1111-D) Automated bioprocess development of an IPTG-inducible E. coli strain

(1114-C) Automated RNA-seq library preparation on the Beckman Coulter Biomek i7 Hybrid Automated Workstation using a shortened KAPA RNA HyperPrep workflow

(1115-D) cfDNA Extraction Simplified: An Automated Workflow on Omega Bio-tek’s Cutting-Edge Platform

(1117-B) Compound Management Establishment in Start-ups and Small Biotech Companies

(1118-C) Generating GFP-expressing CHO-K1 cell lines using the Tecan UNO Single Cell Dispenser

(1119-D) High-quality RNA libraries generated on the Agilent Bravo NGS Workstation with a new, shorter RNA library prep workflow with rRNA depletion

(1121-B) High-throughput preparation of NGS libraries for target-enriched DNA sequencing (whole exome sequencing) on the Biomek i7 Hybrid Workstation

(1123-D) Implementation of automation to overcome matrix interference in a PK assay for a targeted immunotherapy, UGN-301

(1124-A) Accelerating Discoveries: A Comprehensive RNA-Based Next Generation Sequencing Library Automation Approach

(1125-B) The Multichannel Verification System (Artel MVS®) by Advanced Instruments Delivers Equivalent Results to the Fluorescence Test Method Utilized by Beckman Coulter Life Sciences to Evaluate the Echo Acoustic Liquid Handler Systems

(1126-C) The pioneering NETSseq platform leverages an automated RNA sequencing workflow to drive innovation in precision medicine against neurodegenerative diseases.

(1127-D) 2^nd gen UP.SIGHT: All-in-one solution for the generation of monoclonal cell lines, from single cell cloning to clone selection

(1136-A) CellXpress.ai Automated Cell Culture System: Automated workstation for reproducible organoid cultivation.

(1140-A) 3D-printed modular parallel reactors to enable photoredox catalysis

(1146-C) Simultaneous 1536x Pipetting: Next-Generation Mass Spectrometry for High-Throughput Screening in Drug Discovery

(1155-D) Engineering a Novel Automated DNA Library Preparation Platform from Peripheral Blood for Next-Generation Sequencing

(1159-D) Advancing Acoustic Ejection Mass Spectrometry: Next-generation platform for high-throughput sample analysis

(1163-D) Automating end-to-end plasmid preparation and functional assays on the Beckman Coulter Biomek i7 Hybrid Workstation

(1165-B) Automating Watchmaker’s High Performance Next-Generation Sequencing Chemistries on the Biomek i7 Liquid Handler for Rapid, High-Throughput Sample-to-Sequence Output

(1170-C) Complete Workflow Automation for High-Throughput Western Blotting in Drug Discovery

(1173-B) Automation of the full workflow for 3D cancer spheroid assays with CellXpress.ai

(1174-C) Automating KAPA EvoPlus library preparation kits on firefly®

(1175-D) Miniaturization of DNA library preparation for Illumina sequencing using automated positive displacement liquid handling

(1180-A) Auto-tRNAseq: Driving throughput in tRNA library generation with firefly®

(1181-B) Improving High-Throughput Automated NGS Library Generation in a Core Sequencing Lab

(1184-A) Optimization of Tagmentation Chemistries and Workflows for Fully Automated Next-Generation Sequencing Library Preparation

(1187-D) Automation of Illumina DNA PCR-Free Prep, Tagmentation Library Construction Kit with Plate-based Unique Dual Indices on the Biomek NGeniuS Next Generation Library Prep System

(1189-B) Miniaturized, fully automated NEBNext Direct Genotyping Solution using the Biomek i7 Hybrid Automated Workstation in conjunction with the Echo 525 Acoustic Liquid Handler for marker-assisted breeding

(1194-C) A customizable electronic solution to automate work orders, staffing assignment, and status tracking

(1200-A) A Magnetic-ELISA (MAG-LISA) High-Throughput robotic platform to perform fast and reliable Immunoassays for Vaccine development

(1201-B) A Multi-purpose Automation System for Large-scale Super-resolution Image Data Acquisition

(1204-A) A sustainable open-source biofoundry platform ready for implementation

(1207-D) Accelerating Drug Discovery at Totus Medicines: DNA-Encoded Library Screening with firefly®

(1208-A) Accelerating Formulation Development by Implementation of High Throughput Screening Workflow

(1212-A) Advancing Autonomous Discovery: Enhancements to the Workcell Execution Interface

(1217-B) An integrated approach to enhancing compound management at Merck

(1221-B) Assessment of cloning efficiency and error rates of various single-cell dispensing technologies

(1224-A) Automated Directed Evolution: A PicoShell Approach

(1225-B) Automated Logging of Process Metrics on a Robotic Liquid Handler: Daily Usage, Run Times, Errors and More

(1226-C) Automated production of human neuromuscular organoids using a customized robotic system.

(1227-D) Automated Screening Workflows with Animal-free Nanofibrillar Cellulose 3D hydrogels

(1228-A) Automated Single-Cell Sequencing Using Evercode Split-Pool Combinatorial Barcoding on a Hamilton Vantage Liquid Handler

(1229-B) Automated workflow for 3D cell model dispensing using spheroONE and phenotypic profiling using Pu·MA System EC

(1231-D) Automating Agrochemical Formulation Development

(1232-A) Automating PacBio® SMRTbell® Prep Kit 3.0 Workflow on the Revvity Sciclone® NGSx G3 Workstation

(1233-B) Automating the CE-SDS and cIEF workflows for downstream analysis on the BioPhase 8800 system

(1234-C) Automating the Illumina Complete Long Read Prep with Enrichment on Revvity Sciclone® G3 NGSx Workstation

(1235-D) Automating the NEXTFLEX® Human Whole Exome Sequencing Panel Target Enrichment workflow on the Revvity Fontus NGS workstation

(1236-A) Automation of microbial environmental monitoring

(1241-B) Bridging the Gap between Industrial and Lab Automation

(1248-A) Comparative Analysis of Gravimetric Technology with Checkit®Go - Capillary Technology for Measuring Dispense Volumes in ALHS

(1249-B) Comparison of Increasingly Automated Versions of an Electrochemiluminescence Assay Method for Regulated Assay Support

(1250-C) Comparison of SDS-PAGE to automated parallel capillary electrophoresis for enzyme size and purity assessments

(1253-B) Custom Software to Bridge the LIMS -Lab Automation Informatics Gap

(1260-A) Developing a global, scalable, modular, and integrated analytical workflow manager tool

(1261-B) Developing Analytical Methods on the Hamilton Vantage 2.0

(1263-D) Development and Evaluation of both an Automated Workflow and the BlueCatBio Blue®Plate Consumable for Flow Cytometry Sample Preparation

(1266-C) Development of a Flexible Platform for the Preparation of Assay-Ready Plates in Drug Hit-to-Lead Processes

(1271-D) Developments in Quadruplexing Microplate Assays: From 1536 to 6444 Assays in a Standard Microplate

(1273-B) Discovering novel biologics via automated high-throughput flow cytometry

(1275-D) dragonfly® discovery: Pioneering Sustainable Liquid Handling in the Modern Laboratory

(1277-B) Enhancing Laboratory Efficiency: Automated Serial Evaporation System

(1279-D) Enhancing Pathogen Surveillance with Automated NGS Library Preparation

(1280-A) Establishing an automated iPSC culture system for large-scale iPSC line banking and improved reproducibility of differentiation protocols into mature cell types

(1286-C) Fit-for-Purpose Validation of Cell Signaling Technology® Antibodies for Simple Western™ on the ProteinSimple Jess™.

(1287-D) FluidCore: An Automated Purification Platform for a Centralized Sample Purification and Processing Workflow

(1291-D) Fully automated iPSC differentiation, expansion and maintenance.

(1292-A) Fully automated maintenance of HEK-293T cells using Mytos for use with cell screening platform

(1300-A) Grenova Purus microplate washer evaluation

(1305-B) High Throughput Reaction Screening at GSK

(1313-B) Holy Crab! Automated Bacterial Endotoxins Platform for Pharmaceutical Quality Control Testing

(1327-D) Integration of Nucleic Acid Sample Quality Assessment in Liquid Handling Workflows with the Colibri Module

(1334-C) Leveraging Hamilton Liquid Handling Capabilities to Enable the High Throughput Preparation of Formulated Agricultural Products for Analysis and Characterization

(1335-D) Leveraging Laboratory Automation for Error Mitigation, Enhanced Safety, and Workflow Efficiency in Clinical Laboratories

(1336-A) Low Cost Automation of RNA Barcoding with the Integra Assist Liquid Handler for the Parse Biosciences Single Cell RNA Sequencing Evercode Workflow

(1343-D) Microfluidic Innovations to Enable Automated Nucleic Acid Detection in the Field

(1347-D) Modern labware identification options that maximize your lab automation and organization.

(1353-B) Open-source, low-cost automation solution for passaging adherent cell cultures in 96-well microplates delivers time savings and more consistent results than manual methods

(1358-C) Picodroplets for cell line development and antibody discovery: accelerating the discovery and development process

(1360-A) Quantitative evaluation of pipetting parameters in cell suspension by liquid handling system

(1368-A) Robotalization of life science with Maholo LabDroid

(1369-B) Robotic Assembly of Microliter Liquid/Gel Chambers for Autonomous Design of Soft Materials

(1385-B) Three Different Liquid Handling Systems to Achieve Flexibility and Scalability in Compound Screening against 400+ Protein Kinases

(1386-C) Tip-Top Cleanup: SPRI Tips for Dynamic PCR Product Cleanup

(1396-A) Walkaway automation of NEBNext UltraShear and Enzymatic Methyl-seq (EM-seq™) on the Revvity Sciclone G3 NGSx iQ workstation

(1400-A) Worklist – Reducing the programming workload written through a liquid handler’s application using a python worklist generator application

(1004-A) A high-throughput gut-on-a-chip model integrating adult stem cell-derived organoids for disease modeling and drug discovery

(1013-B) An vascularized melanoma model for with unidirectional perfusion of circulating immune cells for Advancing Immune-Oncology Research

(1022-C) Characterizing a Developmental Clock in Human and Porcine Models: A Pluripotent Stem Cell Approach

(1109-B) Enabling High-throughput 3D Cell-based Assays with Commercially-available Sources of Human iPSC-derived Cell Types

(1129-B) Differentiation of multiple iPSC lines to different cell types to enable cohort analysis in neurodegeneration: challenges and learnings

(1143-D) CRISPR-Ready ioGlutamatergic Neurons: a functional genomics tool to easily generate disease-specific models for drug discovery and development

(1151-D) Large-scale Generation of Human iPSC-derived Sensory Neurons for Pain Research

(1168-A) Initial osteoblast cell response to keratin-coated titanium.

(1178-C) Applications of MultiDots in Human iPSC-derived Microglia

(1186-C) Rapid and consistent generation of functional motor neurons from reprogrammed human iPSCs using opti-ox technology

(1188-A) Optimizing culture conditions for cardiac organoids to enhance their health and minimize necrotic patterns

(1190-C) 3D organoid assays for compound screening and optimization

(1243-D) Cell Growth and Maintenance of Undifferentiated State in Microcarrier Culture System for Human Induced Pluripotent Stem Cells using Laminin 511E8 Fragment

(1264-A) Development of a composable permeable membrane support

(1281-B) Establishment and upscaling of iPSC-derived Macrophages differentiation protocol and comparison with other macrophage cellular models

(1298-C) Generation of Human Endothelial Cells for Integration of Pericytes and Regional Specific Astrocytes to Mimic in vitro Blood Brain Barrier Model from Human Induced Pluripotent Stem Cells

(1330-C) Label-free morphological profiling and isolation of immune cell subsets using VisionSort, a novel, AI-based flow cytometry platform

(1331-D) Label-free morphometric characterization of T cells for cell and gene therapy research and development

(1348-A) Multiplexed drug and immune cell screening in 3D patient-derived tumoroid models

(1355-D) Patch clamp and HD-MEA profiling the functional properties of human iPSC-derived nociceptors

(1357-B) Physiologically Relevant Human Intestinal Organoids for 3D Drug Screening

(1367-D) Reporter Systems for Live Imaging of iPSC-Derived Neuronal Cells

(1395-D) Visium HD: Spatially Resolved, Single-Cell Scale Gene Expression Mapping of FFPE Tissue

(1401-B) Drastically Accelerated Directed Differentiation of Human Pluripotent Stem Cells into Melanocytes for Phenotypic Screening

(1405-B) Multiplex analysis of Predictive Oncology’s 3D tumor models using Tecan’s Spark® Cyto imaging multimode reader

(1011-D) Advancing Phenotypic Drug Hunting: AI for Biologists

(1045-B) Exploring relationships of gene function and chemical regulators using JUMP Cell Painting Consortium data

(1130-C) A machine learning-assisted image-based profiling methodology for phenotypic drug discovery

(1137-B) Label-free High-Throughput Viability Analysis using Advanced Machine Learning Algorithms

(1162-C) Nuclei Segmentation on Brightfield Images using a pre-trained Artificial Intelligence (AI) Model

(1197-B) A Graphical User Interface for ML-Based Modeling of Single-Cell and Well-Level Imaging Data

(1206-C) Absolute quantification of polar analytes using machine learning and StandardCandlesTM as universal calibrators

(1218-C) Application of parallel machine learning methodologies to surface mechanistically distinct classes of compound hits in a high-content imaging screen for inflammasome inhibitors

(1230-C) Automatic Assignment of Biacore SPR and Octet BLI Kinetic Binding Curve Profiles with Artificial Intelligence.

(1254-C) Deciphering Cellular Mechanisms through Phenotype: CRISPR-Induced Perturbations Analyzed through Cell Painting and Machine Learning

(1256-A) Deep Learning-based Morphological Profiling as a Screening Method for Human Macrophage Polarization Modulators

(1274-C) DiscoveryAI SAFIRE: a collection of machine learning models to predict ADMET liabilities for small molecule drug discovery

(1321-B) Informatics resources and databases to support identification of E3 ligase ligands using machine learning

(1338-C) Mastering complex challenges in controlled substance compliance using advanced Markush and similarity search technologies

(1350-C) NCATS OpenData Portal: a scalable open science platform to share and explore SARS-CoV-2 screening data

(1371-D) Scalable Instrument Data Management and Integration Using Standards and Patterns

(1373-B) Scheduling methods for streamlining and designing laboratory automation

(1036-A) Colony Picking to Directed Evolution: High-Throughput Functional Screening with Hollow Hydrogel Microparticles

(1040-A) Colorimetric analysis of aluminum present in deodorants using a paper-based microfluidic device

(1060-A) High aspect ratio nanostraws for high throughput primary immune cell transfection

(1079-D) A scalable liquid handling platform for high-throughput manipulation of live cell-based assays

(1096-A) Pushing Boundaries in Cancer Research and Treatment: Innovations in the multi-Organ-on-Chip (multi-OoC) approach

(1112-A) Tuna-step: Tunable Parallelized Step Emulsification for the Generation of Droplets with Dynamic Volume Control to 3D Print Functionally Graded Porous Materials

(1148-A) Development of a sticker sealed microfluidic device for in situ analytical measurements using synchrotron radiation

(1160-A) Gravity Assisted Processing of Whole Blood for Amphetamine Analysis in a Point of Care Limited Access Facility

(1176-A) Nanoimpact- Comparative study on biogenic synthesis and Market procured CuO NPs and FeO NPs on rice plant.

(1177-B) Nanopollution- Inhibitory effect of CuO NPs in tolerant and susceptible variety of rice (Oryza sativa L.) with conflicting levels of stress tolerance.

(1203-D) A Study on Nanofiber and Microfiber Composite Structures in Tissue Engineering

(1342-C) Microfluidic in vitro systems for neurological disease modeling under electrical stimulation

(1058-C) Novel Platform for Full-Scale Single-Cell Biology through Laser Particle Barcoding of Individual Cells

(1238-C) Biophysical and Biochemical Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders

(1240-A) Bispecific Antibody Discovery Platform for IND Enabling Studies – Case Study of HER-2/NKG2D Bispecific Antibody

(1341-B) Methotrexate-based dihydrofolate reductase-specific degraders

(1016-A) A strategy for comparing in vitro ‘omic technologies to existing rat in vivo data

(1051-D) Leveraging high throughput targeted proteomics to impact a protein degrader project at AstraZeneca

(1085-B) Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA DICTrank

(1131-D) Automation Revolution: Streamlined Sample Collection and DNA Extraction for High-Throughput Microbiome Analysis

(1133-B) Moving towards patient-centric clinical trials with metabolomics analysis of dried blood samples using an at-home microsampling collection device

(1145-B) Ancient Genomics: Semi-automated High-Throughput Workflow for the Preparation of NGS Libraries

(1164-A) Identification of a Potential Vaccine against TreponemaPallidum Using Subtractive Proteomics andReverse-Vaccinology Approaches

(1210-C) Advances in multimodal image data management in OMERO Plus: connecting tissues, cells, sequences, and features

(1378-C) Synergies in automated sample preparation and short gradient LC-MS acquisition advances high-throughput discovery proteomics.

(1382-C) The Darwin Tree of Life project: Achieving large-scale whole genome sequencing through automated library construction at the Wellcome Sanger Institute

(1388-A) Towards high-throughput low-cost sustainable ecotoxicity testing

(1030-C) A continuous kinetic assay to quantitate specific protein kinase activity in unfractionated cell lysates

(1049-B) Fully-Automated Extraction of High-Quality Total Nucleic Acids from FFPE specimens using Covaris® truXTRAC® FFPE SMART Solutions and Hamilton Robotics

(1080-A) NanoBeacon.AI: AI-enhanced nanodiamond biosensor for automated sensitivity prediction to oxidative phosphorylation inhibitors

(1082-C) Automating cell-free and formalin-fixed paraffin-embedded DNA library preparation for Next Generation Sequencing workflows on the Biomek® NGeniuS® System

(1083-D) Implementation of Laboratory Automation to Support Scaling of Cancer Patients Testing using OmniSeq® INSIGHT Molecular Diagnostic Test

(1088-A) Optimization of DNA methyltransferase inhibitors-based combination through quadratic phenotypic optimization platform (QPOP) to target the epigenome of gastric cancer

(1120-A) Using a high-throughput drug optimization platform to optimize patient-specific drug treatments for aortic valve stenosis

(1134-C) Automated Tissue Dissection Solution to Support Comprehensive Genomic and Immune Profiling

(1135-D) Establishment of a quality-driven manufacturing process to reprogram human donor material into human induced pluripotent stem cells to support drug discovery.

(1359-D) Porosome Therapeutics Inc., has Developed Therapy to Rescue Cystic Fibrosis by Reprogramming the Porosome Secretory Machinery